KMID : 0614620000350030301
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Korean Journal of Gastroenterology 2000 Volume.35 No. 3 p.301 ~ p.308
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Histopathologic Analysis according to Depth of invasion in Early Gastric Cancer with Submucosal Invasion
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Hong Sok-Kyun
Lim Chang-Young Kang Nam-Young Choi Jeong Song Il-Han Kim Jung-Won Roe Im-Hwan Go Jai-Hyang Jung Min
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Abstract
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Background/Aims : We determined the possibility of endosocpic mucosal resection in early gastric cancer with submucosal (sm) invasion, especially carcinoma in which the depth of invasion is limited within superficial.
Methods : We retrospectively reviewed 35 cases of early gastric carcinoma with submucosal invasion resected by subtotal or total gastrectomy from 1997 through 1998. We analyzed several histopathological factors in relation to degree of submucosal invasion through final pathologic reports. Degree of sm invasion was designated as follows: sm1- the depth of invasion was limited within superficial, one third of the sm layer: sm2- the invasion was limited within two third of sm layer; sm3- the invasion was limited within distal one third of sm layer.
Results : On analysis of the degree of carcinoma invasion into the ´À layer, the rate of lymph node metastasis in sm1, sm2, 2m3, and sm2+3 were 16.7%, 33.3%, 17.6%, and 21.7%, respectively. The rates of lymphatic ducts or vessels permeation in sm1, sm2, sm3, and sm2+3 were 25%, 33.3%, 11.2%, and 17.4%, respectively. The frequencies of poorly differentiated carcinoma in sm1, sm2, 2m3, and sm2+3 were 16.7%, 33.3%, 52.9%, and 47.8%, respectively.
Conclusions : Poorly differentiated carcinoma and lymph node metastasis were observed less often in sm1 than in sm2 and sm3.
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KEYWORD
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SM-carcinoma, Grade of depth of invasion, Endoscopic mucosal resetion,
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